Levomilnacipran (Fetzima): A New SNRI for Depression
Levomilnacipran (Fetzima): A New SNRI for Depression
December 23, 2013 (Issue: 1432)
The FDA has approved levomilnacipran (lee" voe mil
na' si pran; Fetzima – Forest), a serotonin and norepinephrine
reuptake inhibitor (SNRI), for treatment of
major depressive disorder. Levomilnacipran is the
more active enantiomer of...more
1. Milnacipran (Savella) for fibromyalgia. Med Lett Drugs Ther 2009; 51:45.
2. Drugs for psychiatric disorders. Treat Guidel Med Lett 2013; 11:53.
3. AL Auclair et al. Levomilnacipran (F2695), a norepinephrine-preferring SNRI: profile in vitro and in models of depression and anxiety. Neuropharmacology 2013; 70:338.
4. GM Asnis et al. Efficacy and safety of levomilnacipran sustained release 40 mg, 80 mg, or 120 mg in major depressive disorder: a phase 3 randomized, double-blind, placebo-controlled study. J Clin Psychiatry 2013; 74:242.
5. D Bakish et al. Levomilnacipran ER 40 mg and 80 mg in patients with major depressive disorder: a phase III, randomized, double-blind, fixed-dose, placebo-controlled study. J Psychiatry Neurosci 2013 October 22 (epub).
6. A Sambunaris et al. A phase III, double-blind, placebo-controlled, flexible-dose study of levomilnacipran extended-release in patients with major depressive disorder. J Clin Psychopharmacol 2013 November 27 (epub).
7. R Mago et al. Safety and tolerability of levomilnacipran ER in major depressive disorder: results from an open-label, 48-week extension study. Clin Drug Investig 2013; 33:761.
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