The Medical Letter on Drugs and Therapeutics
FROM
ISSUE 1576
ISSUE 1576
July 15, 2019
Issue 1576
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Drugs for Smoking Cessation
July 15, 2019 (Issue: 1576)
Smoking tobacco remains the primary preventable
cause of death in the US. Smoking cessation often requires
both pharmacotherapy and behavioral support.
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- Varenicline (Chantix) for tobacco dependence. Med Lett Drugs Ther 2006; 48:66.
- EJ Mills et al. Comparisons of high-dose and combination nicotine replacement therapy, varenicline, and bupropion for smoking cessation: a systematic review and multiple treatment meta-analysis. Ann Med 2012; 44:588.
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- TB Baker et al. Effects of nicotine patch vs varenicline vs combination nicotine replacement therapy on smoking cessation at 26 weeks: a randomized clinical trial. JAMA 2016; 315:371.
- AS Gershon et al. Cardiovascular and neuropsychiatric events after varenicline use for smoking cessation. Am J Respir Crit Care Med 2018; 197:913.
- D Kotz et al. Cardiovascular and neuropsychiatric risks of varenicline: a retrospective cohort study. Lancet Respir Med 2015; 3:761.
- JR Hughes. Varenicline as a cause of suicidal outcomes. Nicotine Tob Res 2016; 18:2.
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- RM Anthenelli et al. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. Lancet 2016; 387:2507.
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- CF Koegelenberg et al. Efficacy of varenicline combined with nicotine replacement therapy vs varenicline alone for smoking cessation: a randomized clinical trial. JAMA 2014; 312:155.
- JO Ebbert et al. Combination varenicline and bupropion SR for tobacco-dependence treatment in cigarette smokers: a randomized trial. JAMA 2014; 311:155.
- JE Rose and FM Behm. Combination varenicline/bupropion treatment benefits highly dependent smokers in an adaptive smoking cessation paradigm. Nicotine Tob Res 2017; 19:999.
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- JA Cunningham et al. Effect of mailing nicotine patches on tobacco cessation among adult smokers: a randomized clinical trial. JAMA Intern Med 2016; 176:184.
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- SD Halpern et al. Randomized trial of four financial-incentive programs for smoking cessation. N Engl J Med 2015; 372:2108.
- C Bullen et al. Electronic cigarettes for smoking cessation: a randomised controlled trial. Lancet 2013; 382:1629.
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- T Alzahrani et al. Association between electronic cigarette use and myocardial infarction. Am J Prev Med 2018; 55:455.
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- ML Goniewicz et al. Comparison of nicotine and toxicant exposure in users of electronic cigarettes and combustible cigarettes. JAMA Netw Open 2018, 1:e185937.
- M Sleiman et al. Emissions from electronic cigarettes: key parameters affecting the release of harmful chemicals. Environ Sci Technol 2016; 50:9644.
- R Goel et al. Highly reactive free radicals in electronic cigarette aerosols. Chem Res Toxicol 2015; 28:1675.
- L Kosmider et al. Carbonyl compounds in electronic cigarette vapors: effects of nicotine solvent and battery output voltage. Nicotine Tob Res 2014; 16:1319.
- ML Goniewicz et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob Control 2014; 23:133.
- A Ghosh et al. Chronic e-cigarette exposure alters the human bronchial epithelial proteome. Am J Respir Crit Care Med 2018; 198:67.
- B Reidel et al. E-cigarette use causes a unique innate immune response in the lung, involving increased neutrophilic activation and altered mucin secretion. Am J Respir Crit Care Med 2018; 197:492.
- WH Lee et al. Modeling cardiovascular risks of e-cigarettes with human-induced pluripotent stem cell-derived endothelial cells. J Am Coll Cardiol 2019; 73:2722.
- T Coleman et al. Pharmacological interventions for promoting smoking cessation during pregnancy. Cochrane Database Syst Rev 2015; 12:CD010078.
- CDC. Outbreak of lung injury associated with the use of e-cigarette, or vaping, products. Available at: https://www.cdc.gov/ tobacco/basic_information/e-cigarettes/severe-lung-disease.html. Accessed November 20, 2019.
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